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Cross-Artifact Impact Register

Version: 1.0.0 Last Updated: 2026-02-15 Status: Complete — Tracks all 90+ artifacts across 8 documentation directories Purpose: Single source of truth for artifact dependencies, cascade update requirements, and cross-reference integrity


Executive Summary

This impact register tracks 90+ artifacts across the CODITECT Bioscience QMS platform documentation suite. It maps dependencies, identifies cascade update requirements, and flags highest-impact documents to prevent inconsistencies across the codebase.

Recent Expansion: The addition of 14 new B.1/B.2 artifacts (competitive intelligence + GTM strategy) has created 37 new cross-artifact dependencies and 22 cascade update requirements across existing documents.

Critical Finding: Market sizing numbers ($4.35B TAM, $412M SAM, $26.3M Y5 target) now appear in 18+ artifacts and MUST remain synchronized.

Highest-Impact Artifacts:

  1. 16-prisma-data-model.md — 23 downstream dependents (all technical artifacts)
  2. market-sizing.md — 18 downstream dependents (all business artifacts)
  3. gtm-foundation.md — 15 downstream dependents (all GTM/revenue artifacts)
  4. 19-state-machine-with-guards.md — 12 downstream dependents (workflow artifacts)
  5. competitive-landscape.md — 11 downstream dependents (positioning artifacts)

1. Complete Artifact Inventory

1.1 Executive Documents (6 artifacts)

#FileLinesCategoryStatusDownstream Deps
01executive-summary.md116ExecutiveLegacy4
02executive-summary-updated.md157ExecutiveActive6
03business-case.md281ExecutiveActive8
04investor-pitch-data.md201ExecutiveActive5
60business-model.md325BusinessActive12
61one-pager-investor-brief.md132ExecutiveActive3

Key Dependencies: All executive documents depend on market-sizing.md, competitive-landscape.md, and gtm-foundation.md for consistent numbers.

1.2 Market & Competitive Documents (20 artifacts)

#FileLinesCategoryGenerated ByDownstream Deps
05market-opportunity.md289MarketManual7
06market-opportunity-deep-dive.md342MarketManual9
07tam-sam-som-analysis.md385MarketManual8
08competitive-moat-analysis.md419MarketManual6
09go-to-market-strategy.md531MarketManual10
10roi-quantification.md278MarketManual5
market-sizing.md599MarketB.1.118
customer-segmentation.md847MarketB.1.211
competitive-landscape.md1284MarketB.1.311
competitive-positioning.md951MarketB.1.49
competitive-executive-brief.md423MarketB.1.54
competitive-battlecards.md1052MarketB.1.66
competitive-monitoring-spec.md736MarketB.1.73
competitive-feature-matrix.md892MarketB.1.87
gtm-foundation.md870GTMB.2.115
gtm-channels.md1088GTMB.2.28
gtm-marketing.md1174GTMB.2.37
gtm-customer-success.md989GTMB.2.46
gtm-execution-plan.md1200GTMB.2.59
gtm-metrics.md1475GTMB.2.68

Critical Consistency Requirements:

  • TAM/SAM/SOM Numbers: $4.35B / $412M / $26.3M (Y5) must match across 05-07, market-sizing.md, gtm-foundation.md, 60-61
  • Pricing Tiers: Startup ($48K), Growth ($120K), Enterprise ($240K), Custom ($500K+) must match across 60, gtm-foundation.md, 71
  • Competitor Names: 10 profiled competitors must match across competitive-landscape.md, competitive-feature-matrix.md, competitive-battlecards.md, 08

1.3 Product Documents (2 artifacts)

#FileLinesCategoryStatusDownstream Deps
11product-roadmap.md217ProductActive8
62unified-execution-plan.md420ProductActive6

1.4 Architecture Documents (6 artifacts)

#FileLinesCategoryStatusDownstream Deps
12sdd.md254ArchitectureActive11
13tdd.md373ArchitectureActive9
14c4-architecture.md341ArchitectureActive7
15mermaid-diagrams.md302ArchitectureActive5
16prisma-data-model.md731ArchitectureActive23
17e-signature-architecture.md504ArchitectureActive8

Critical Note: 16-prisma-data-model.md is the highest-impact technical artifact — changes here cascade to all dashboards, API endpoints, and state machines.

1.5 State Machine Documents (2 artifacts)

#FileLinesCategoryStatusDownstream Deps
18state-machine-specification.md428State MachineActive8
19state-machine-with-guards.md512State MachineActive12

1.6 Compliance Documents (6 artifacts)

#FileLinesCategoryStatusDownstream Deps
20regulatory-compliance-matrix.md645ComplianceActive9
21rbac-model.md387ComplianceActive7
22rbac-permissions-matrix.md519ComplianceActive11
23architecture-decision-records.md298ComplianceActive4
58gap-analysis-framework.md823ComplianceActive5
compliance-readiness-matrix.md412ComplianceActive6

1.7 Agent Documents (3 artifacts)

#FileLinesCategoryStatusDownstream Deps
24agent-orchestration-mapping.md356AgentsActive4
25agent-orchestration-spec.md489AgentsActive6
26agent-message-contracts.md521AgentsActive5

1.8 Reference Documents (5 artifacts)

#FileLinesCategoryStatusDownstream Deps
27coditect-impact.md267ReferenceActive3
28quick-start-guide.md189ReferenceActive2
29glossary.md745ReferenceActive15
30document-inventory.md423ReferenceActive2
31website-plan.md531ReferenceActive4

1.9 Operations Documents (13 artifacts)

#FileLinesCategoryStatusDownstream Deps
63data-architecture.md359OperationsActive8
64security-architecture.md421OperationsActive9
65testing-strategy.md433OperationsActive6
66operational-readiness.md541OperationsActive7
66bmulti-site-management.md378OperationsActive4
67integration-api-strategy.md477OperationsActive5
68user-experience-journeys.md504OperationsActive6
69versioning-evolution-strategy.md511OperationsActive4
70validation-protocol-templates.md492OperationsActive7
71api-endpoint-specification.md687EngineeringActive12
72deployment-architecture.md543DevOpsActive8
73event-catalog.md621EngineeringActive10
74capa-workflow.md589ComplianceActive9
75audit-readiness-guide.md634ComplianceActive8

Total Artifact Count: 90+ documents (including dashboards, prompts, and other supporting files not shown in detail)


2. Dependency Graph

2.1 Foundation Layer (Foundation → Technical)

All technical artifacts depend on these foundational documents:

16-prisma-data-model.md ────────────► ALL technical artifacts (23 deps)
├──► 71-api-endpoint-specification.md
├──► 73-event-catalog.md
├──► 74-capa-workflow.md
├──► 12-sdd.md
├──► 13-tdd.md
├──► 63-data-architecture.md
└──► All 30+ dashboards (.jsx files)

19-state-machine-with-guards.md ───► Workflow artifacts (12 deps)
├──► 71-api-endpoint-specification.md (transitions)
├──► 73-event-catalog.md (state events)
├──► 74-capa-workflow.md (CAPA states)
├──► 18-state-machine-specification.md
└──► All state machine dashboards

22-rbac-permissions-matrix.md ─────► Security artifacts (11 deps)
├──► 71-api-endpoint-specification.md (auth per endpoint)
├──► 74-capa-workflow.md (CAPA permissions)
├──► 75-audit-readiness-guide.md (auditor permissions)
├──► 64-security-architecture.md
└──► All compliance dashboards

2.2 Business Layer (Market Data → Revenue → Financials)

market-sizing.md (B.1.1) ──────────► Business artifacts (18 deps)
\$4.35B TAM ├──► 05-market-opportunity.md
\$412M SAM ├──► 06-market-opportunity-deep-dive.md
\$26.3M Y5 target ├──► 07-tam-sam-som-analysis.md
├──► 60-business-model.md
├──► 61-one-pager-investor-brief.md
├──► 02-executive-summary-updated.md
├──► 03-business-case.md
├──► 04-investor-pitch-data.md
├──► gtm-foundation.md
├──► gtm-execution-plan.md
├──► gtm-metrics.md
└──► All revenue dashboards

gtm-foundation.md (B.2.1) ─────────► GTM artifacts (15 deps)
4-tier pricing model ├──► gtm-channels.md
\$48K-\$500K+ ACV ├──► gtm-marketing.md
LTV:CAC 5x target ├──► gtm-customer-success.md
├──► gtm-execution-plan.md
├──► gtm-metrics.md
├──► 09-go-to-market-strategy.md
├──► 60-business-model.md
├──► 66-operational-readiness.md
├──► 71-api-endpoint-specification.md (pricing API)
└──► All revenue dashboards

competitive-landscape.md (B.1.3) ──► Positioning artifacts (11 deps)
10 competitor profiles ├──► competitive-positioning.md
Feature matrix ├──► competitive-feature-matrix.md
Pricing benchmarks ├──► competitive-battlecards.md
├──► competitive-executive-brief.md
├──► competitive-monitoring-spec.md
├──► 08-competitive-moat-analysis.md
├──► gtm-foundation.md (competitive pricing)
├──► gtm-marketing.md (messaging)
└──► All competitive dashboards

2.3 Compliance Layer (Regulatory → Audit → Validation)

20-regulatory-compliance-matrix.md ─► Compliance artifacts (9 deps)
├──► 75-audit-readiness-guide.md
├──► 70-validation-protocol-templates.md
├──► 74-capa-workflow.md (21 CFR 820.90/820.198)
├──► compliance-readiness-matrix.md
└──► All compliance dashboards

17-e-signature-architecture.md ────► Approval artifacts (8 deps)
├──► 71-api-endpoint-specification.md (approval endpoints)
├──► 74-capa-workflow.md (CAPA approvals)
├──► 75-audit-readiness-guide.md (§11.70 compliance)
└──► All signature/approval dashboards

3. Impact Matrix: B.1/B.2 New Artifacts → Existing Artifacts

This section identifies every existing artifact that requires updates due to the 14 new B.1/B.2 artifacts.

3.1 Critical Updates (Changes Meaning or Accuracy)

Existing ArtifactImpacted ByRequired UpdatePriorityStatus
05-market-opportunity.mdmarket-sizing.md (B.1.1)Update TAM/SAM/SOM to match $4.35B/$412M/$26.3MP0
06-market-opportunity-deep-dive.mdmarket-sizing.md (B.1.1)Reconcile market data with 12-source triangulationP0
07-tam-sam-som-analysis.mdmarket-sizing.md (B.1.1)Full replacement or supersession noticeP0
08-competitive-moat-analysis.mdcompetitive-landscape.md (B.1.3)Update 10-competitor landscape, add new entrantsP0
09-go-to-market-strategy.mdgtm-foundation.md (B.2.1)Reconcile GTM motion (hybrid sales-led vs. prior strategy)P0
10-roi-quantification.mdcustomer-segmentation.md (B.1.2)Update ROI by segment (startup/growth/enterprise/custom)P1
60-business-model.mdgtm-foundation.md (B.2.1)Reconcile pricing tiers ($48K/$120K/$240K/$500K+)P0
60-business-model.mdmarket-sizing.md (B.1.1)Update TAM/SAM/SOM referencesP0
61-one-pager-investor-brief.mdAll B.1/B.2 artifactsComprehensive refresh with new market + GTM dataP1
71-api-endpoint-specification.mdgtm-foundation.md (B.2.1)Add subscription tier validation to pricing endpointsP1
66-operational-readiness.mdgtm-customer-success.md (B.2.4)Add customer success cost model ($85K/yr QA Director)P1

3.2 Reference Updates (Cross-Reference Additions)

Existing ArtifactImpacted ByRequired UpdatePriorityStatus
02-executive-summary-updated.mdAll B.1/B.2 artifactsUpdate competitive landscape + GTM sectionsP2
03-business-case.mdmarket-sizing.md, gtm-foundation.mdAdd market sizing + revenue model referencesP2
04-investor-pitch-data.mdmarket-sizing.md, competitive-landscape.mdUpdate pitch deck data pointsP2
11-product-roadmap.mdcompetitive-feature-matrix.md (B.1.8)Add competitive feature parity milestonesP2
12-sdd.mdgtm-foundation.md (B.2.1)Reference subscription tier technical requirementsP2
29-glossary.mdAll B.1/B.2 artifactsAdd new acronyms: ICP, ACV, NRR, CAC, LTV, G2MP2
30-document-inventory.mdAll B.1/B.2 artifactsAdd 14 new artifacts to inventoryP1
31-website-plan.mdAll B.1/B.2 artifactsAdd navigation for Market Intelligence sectionP2
62-unified-execution-plan.mdgtm-execution-plan.md (B.2.5)Reconcile GTM timeline with product timelineP1

3.3 Dashboard Resynchronization

DashboardData Source ChangeRequired UpdatePriorityStatus
49-revenue-model-dashboard.jsxgtm-foundation.md (B.2.1)Update pricing tiers, ACV, unit economicsP0
47-market-opportunity-dashboard.jsxmarket-sizing.md (B.1.1)Update TAM/SAM/SOM, CAGR, Y1-Y5 targetsP0
48-tam-sam-som-dashboard.jsxmarket-sizing.md (B.1.1)Full resync with new market dataP0
54-competitive-comparison.jsxcompetitive-landscape.md (B.1.3)Add 10 competitors, feature matrix, pricingP1
55-competitive-positioning-canvas.jsxcompetitive-positioning.md (B.1.4)Update positioning map coordinatesP1
56-gtm-execution-timeline.jsxgtm-execution-plan.md (B.2.5)Add phase-gate milestonesP1
57-customer-success-metrics.jsxgtm-customer-success.md (B.2.4)Add NPS, retention, expansion metricsP1

3.4 Consistency Reconciliation (Number Synchronization)

Data PointSource of TruthMust Match InCurrent Status
TAM 2026market-sizing.md05, 06, 07, 60, 61, 47, 48☐ Pending sync
SAM 2026market-sizing.md05, 06, 07, 60, 61, 47, 48☐ Pending sync
SOM Y5 Targetmarket-sizing.md60, 61, gtm-foundation.md, gtm-metrics.md☐ Pending sync
Startup Tier ACVgtm-foundation.md60, 71, 49☐ Pending sync
Growth Tier ACVgtm-foundation.md60, 71, 49☐ Pending sync
Enterprise Tier ACVgtm-foundation.md60, 71, 49☐ Pending sync
Custom Tier ACVgtm-foundation.md60, 71, 49☐ Pending sync
LTV:CAC Ratiogtm-foundation.md60, gtm-metrics.md, 49☐ Pending sync
Gross Margingtm-foundation.md60, 66, gtm-metrics.md☐ Pending sync
Competitor Countcompetitive-landscape.md08, 54, 55, battlecards, feature-matrix☐ Pending sync

4. B.1/B.2 New Artifact Impact Analysis

4.1 Market Sizing Impact (B.1.1)

Artifact: market-sizing.md (599 lines) Confidence: HIGH Methodology: 12-source triangulation, top-down + bottom-up validation

Downstream Impact:

  • 18 artifacts reference TAM/SAM/SOM numbers
  • 7 dashboards visualize market data
  • CRITICAL: All prior market estimates (ranging $1.6B-$31.3B) must be reconciled or deprecated

Cascade Updates Required:

  1. Replace or supersede 07-tam-sam-som-analysis.md (old analysis)
  2. Update 05, 06 with new market framework
  3. Sync 60, 61, 02, 03, 04 executive documents
  4. Regenerate 47, 48 market dashboards

4.2 Customer Segmentation Impact (B.1.2)

Artifact: customer-segmentation.md (847 lines) Segments: Startup, Growth, Enterprise, Custom ICP: FDA-regulated life sciences, 50-5000 employees, cloud-ready

Downstream Impact:

  • 11 artifacts reference customer segments
  • Pricing strategy in gtm-foundation.md aligned to segments
  • ROI calculations in 10-roi-quantification.md must segment

Cascade Updates Required:

  1. Update 10-roi-quantification.md with per-segment ROI
  2. Align 60-business-model.md customer taxonomy
  3. Update 68-user-experience-journeys.md with segment personas

4.3 Competitive Landscape Impact (B.1.3)

Artifact: competitive-landscape.md (1284 lines) Competitors Profiled: 10 (Veeva, MasterControl, Greenlight Guru, TrackWise, ETQ, ComplianceQuest, Qualio, Arena, AssurX, Siemens) Data: Feature matrix, pricing, market share, SWOT, funding

Downstream Impact:

  • 11 artifacts reference competitive data
  • 4 dashboards visualize competitive positioning
  • Messaging strategy in gtm-marketing.md depends on differentiation

Cascade Updates Required:

  1. Update 08-competitive-moat-analysis.md with new competitor data
  2. Regenerate 54-competitive-comparison.jsx dashboard
  3. Sync competitive-battlecards.md, competitive-feature-matrix.md
  4. Update gtm-marketing.md messaging based on competitive gaps

4.4 GTM Foundation Impact (B.2.1)

Artifact: gtm-foundation.md (870 lines) GTM Motion: Hybrid Sales-Led Enterprise + PLG evaluation Pricing: 4-tier SaaS ($48K-$500K+ ACV) Unit Economics: LTV:CAC >5x (Y1), 75-82% gross margin, 6-12mo payback

Downstream Impact:

  • 15 artifacts reference revenue model or pricing
  • All GTM artifacts (B.2.2-B.2.6) depend on this foundation
  • API specification must validate subscription tiers

Cascade Updates Required:

  1. Reconcile 60-business-model.md pricing tiers
  2. Update 71-api-endpoint-specification.md pricing/subscription endpoints
  3. Sync 09-go-to-market-strategy.md with hybrid sales-led motion
  4. Regenerate 49-revenue-model-dashboard.jsx
  5. Update 66-operational-readiness.md cost model

4.5 GTM Execution Plan Impact (B.2.5)

Artifact: gtm-execution-plan.md (1200 lines) Timeline: 18-month phased rollout (Design Partner → Pilot → Scale) Phase Gates: 9 milestones from DP selection to $4.2M ARR

Downstream Impact:

  • 9 artifacts reference GTM timeline
  • Product roadmap must align with GTM phases
  • Operational readiness must match GTM hiring plan

Cascade Updates Required:

  1. Reconcile 11-product-roadmap.md with GTM timeline
  2. Update 62-unified-execution-plan.md to merge product + GTM
  3. Sync 66-operational-readiness.md hiring timeline
  4. Generate 56-gtm-execution-timeline.jsx dashboard

5. Gap Closure Status (from Prompt 78)

This section tracks the 28 gaps identified in artifact 58-gap-analysis-framework.md and their resolution status across the 90+ artifact suite.

5.1 Security & Compliance Gaps (G01-G15)

GapDescriptionAddressed ByStatusEvidence
G01Credential Vault Integration64-security-architecture.md §4, 72 §6Vault API spec
G02§11.70 Cryptographic Signature Binding17-e-signature-architecture.mdHMAC + PKI
G03Audit Trail Hash Chain73-event-catalog.md §4.2SHA-256 chain
G04Agent Message Signing64-security-architecture.md §6Ed25519 signing
G05§11.100(b) Re-Authentication64-security-architecture.md §2Session timeout
G06Personnel Training Integration75-audit-readiness-guide.md §2⚠️Reference only
G07Written Policies & Accountability75-audit-readiness-guide.md §6⚠️Template only
G08FDA Compliance Completeness75-audit-readiness-guide.md §3Full CFR map
G09PHI Detection Scanner73-event-catalog.md §4.4Event-driven scan
G10HIPAA Break-Glass Emergency64-security-architecture.md §2Emergency access
G11Session Management & Auto-Logoff64-security-architecture.md §215min timeout
G12HIPAA Completeness75-audit-readiness-guide.md §4Full §164.312
G13SIEM Integration64-security-architecture.md, 72 §7Datadog + Splunk
G14Incident Response WO Generation66-operational-readiness.md §9Auto-WO trigger
G15Access Deprovisioning64-security-architecture.md §3, 75 §4Automated revoke

5.2 CAPA & Risk Management (G16)

GapDescriptionAddressed ByStatusEvidence
G16Risk Assessment & CAPA74-capa-workflow.mdFull 589-line artifact

5.3 Technical Gaps (G17-G18)

GapDescriptionAddressed ByStatusEvidence
G17Optimistic Locking71-api-endpoint-specification.md §2.4version field
G18Dependency DAG Cycle Detection71-api §5.2hasCycles field

5.4 Scaling & Optimization Gaps (G19-G26)

GapDescriptionAddressed ByStatusEvidence
G19Partial Master WO CompletionNot yet addressedPhase G deferred
G20Vendor WO Timeout & EscalationNot yet addressedPhase G deferred
G21Vendor Coordination Portal67-integration-api-strategy.md⚠️Partial reference
G22Vendor IQ/OQ/PQ Upload70-validation-protocol-templates.md §8Upload workflow
G23Experience & Certification Expiry73-event-catalog.md §6.2Expiry event
G24Batch WO Creation71-api future roadmap⚠️Noted, not spec'd
G25Schedule Constraint SolverNot addressedPhase G deferred
G26Resource OptimizationNot addressedPhase G deferred

5.5 Meta Gaps (G27-G28)

GapDescriptionAddressed ByStatusEvidence
G27Artifact Gap Status UpdatesThis document (B.3.1)§5 gap closure
G28Dashboard Data Sync§3.3, §6 above⚠️Identified, not fixed

Summary: 20/28 fully specified (71%), 5/28 partially addressed (18%), 3/28 deferred to Phase G (11%)


6. Finalization Checklist (Execute After All Generation Complete)

6.1 Data Consistency Pass

  • TAM/SAM/SOM numbers consistent across: 05, 06, 07, market-sizing.md, 60, 61, 47, 48, 49, gtm-foundation.md, gtm-metrics.md
  • Pricing tiers ($48K/$120K/$240K/$500K+) consistent across: 60, gtm-foundation.md, 71, 49
  • Competitor names (10 profiled) consistent across: 08, competitive-landscape.md, competitive-feature-matrix.md, competitive-battlecards.md, 54, 55
  • Customer segments (Startup/Growth/Enterprise/Custom) consistent across: customer-segmentation.md, gtm-foundation.md, 10, 60, 68
  • Role names consistent across: 21, 22, 71, 74, 75
  • State names consistent across: 18, 19, 34, 37, 71, 73
  • Entity names consistent across: 16, 35, 36, 71, 73, 74

6.2 Cross-Reference Integrity

  • Every artifact's "Cross-Reference" or "Referenced By" section includes all new B.1/B.2 dependencies
  • No artifact references a non-existent artifact number
  • All "Superseded" or "Deprecated" artifacts are clearly marked
  • All B.1/B.2 artifacts have generated_by and referenced_by frontmatter

6.3 Dashboard Data Sync

  • All JSX dashboards reflect current artifact data (not stale pre-B.1/B.2 data)
  • Market dashboards (47, 48) show $4.35B TAM, $412M SAM, $26.3M Y5
  • Revenue dashboard (49) shows 4-tier pricing model
  • Competitive dashboards (54, 55) show 10 competitors
  • GTM dashboard (56) shows 18-month phased execution plan

6.4 Glossary Completeness

  • Every acronym in B.1/B.2 artifacts appears in 29-glossary.md
  • New terms: ICP, ACV, NRR, CAC, LTV, G2M, PLG, SMB, MM, ENT
  • Version number updated, total term count updated

6.5 Inventory & Navigation

  • 30-document-inventory.md reflects all 90+ artifacts (including B.1/B.2)
  • 31-website-plan.md includes navigation for "Market Intelligence" section
  • B.1/B.2 artifacts have proper category tags (market, gtm, competitive)
  • All artifacts have proper type, component_type, version, status frontmatter

6.6 Meta-Prompt Validation

  • Prompt templates reference correct artifact numbers (not stale references)
  • B.1/B.2 generation prompts in prompts/ directory are marked complete
  • This impact register (B.3.1) is marked as authoritative source for dependencies

7. Known Technical Debt

ItemDescriptionEffortPriorityOwner
Stale TAM/SAM numbersArtifacts 05-07 have inconsistent market sizing vs. market-sizing.mdMP0TBD
Duplicate pricing models60-business-model.md vs. gtm-foundation.md have overlapping pricing sectionsSP1TBD
Dashboard-artifact couplingDashboards hardcode data; no automated sync from markdownLP2TBD
Competitor count variance08-competitive-moat-analysis.md mentions 8 competitors, competitive-landscape.md has 10SP1TBD
GTM strategy reconciliation09-go-to-market-strategy.md pre-dates gtm-foundation.md; motion may differMP0TBD
Missing JSX for B.1/B.2New artifacts (market-sizing, competitive-landscape, gtm-*) have no dedicated dashboardsLP2TBD
G19, G20, G24-G26 gaps5 Phase G gaps deferred — no artifacts address theseLP3Phase G

8. Highest-Impact Artifacts (Change Amplification)

These artifacts have the most downstream dependents. Changes here require broad cascade updates:

Tier 1: Critical Infrastructure (20+ dependents)

ArtifactDependentsImpact Scope
16-prisma-data-model.md23ALL technical artifacts, dashboards, API specs
market-sizing.md18ALL business/financial artifacts, exec docs, dashboards

Tier 2: Major Components (10-19 dependents)

ArtifactDependentsImpact Scope
gtm-foundation.md15GTM strategy, revenue model, pricing, unit economics
19-state-machine-with-guards.md12Workflow artifacts, API transitions, event catalog
competitive-landscape.md11Positioning, messaging, pricing, feature matrix
22-rbac-permissions-matrix.md11Security, compliance, API auth, dashboards
customer-segmentation.md11Pricing, ROI, GTM, personas, journeys
71-api-endpoint-specification.md12All API consumers, frontend, integrations

Tier 3: Moderate Impact (6-9 dependents)

ArtifactDependentsImpact Scope
20-regulatory-compliance-matrix.md9Compliance artifacts, audit readiness, CAPA
competitive-positioning.md9Messaging, battlecards, GTM, dashboards
gtm-execution-plan.md9Product roadmap, hiring, ops readiness
73-event-catalog.md10Event-driven architecture, agents, audit trails
74-capa-workflow.md9Compliance, data model, state machine, RBAC

Change Management Recommendation: Any change to Tier 1-2 artifacts MUST trigger a cascade update review using this impact register.


9. Dependency Validation Rules

9.1 Automated Checks (Proposed)

These checks should be automated via pre-commit hooks or CI/CD:

  1. Dollar Amount Format: All dollar amounts use \$ (backslash-dollar), not $
  2. TAM/SAM/SOM Consistency: Grep all artifacts for TAM/SAM/SOM, ensure they match market-sizing.md
  3. Pricing Tier Consistency: Grep for pricing tiers ($48K, $120K, $240K, $500K), ensure they match gtm-foundation.md
  4. Competitor Name Consistency: Grep for competitor names, ensure count and spelling match competitive-landscape.md
  5. Cross-Reference Integrity: Parse referenced_by frontmatter, ensure no dangling references
  6. Artifact Count: Count all .md files, ensure 30-document-inventory.md matches

9.2 Manual Review Triggers

These changes require manual impact assessment:

  • Market sizing change (TAM/SAM/SOM) → Review all 18 dependent artifacts
  • Pricing tier change → Review 60, 71, gtm-foundation.md, dashboards
  • Data model change (16-prisma-data-model.md) → Review all 23 technical artifacts
  • State machine change (19) → Review workflow artifacts, API, event catalog
  • Competitor addition/removal → Review all competitive artifacts + dashboards

10. Usage Instructions

10.1 When to Consult This Register

  • Before modifying any Tier 1-2 artifact — check downstream impact
  • After adding a new artifact — update inventory, add dependency edges
  • During context compaction recovery — this is your source of truth for what's connected
  • Before generating dashboards — ensure data sources are current
  • During investor pitch prep — verify number consistency across exec docs

10.2 How to Update This Register

  1. After adding a new artifact:

    • Add to §1 inventory with line count, category, status
    • Add dependency edges to §2 dependency graph
    • Calculate downstream dependents
    • Add to §7 technical debt if any gaps created
  2. After modifying a high-impact artifact:

    • Identify all downstream dependents from §8
    • Create cascade update tickets
    • Track completion in §6 finalization checklist
  3. After closing a gap:

    • Update §5 gap closure status
    • Mark with ✅ and evidence

10.3 Maintenance Cadence

  • Weekly: Update §6 finalization checklist progress
  • Monthly: Validate dependency graph accuracy
  • Quarterly: Audit for stale references, update technical debt
  • Per-release: Full consistency pass across all artifacts

11. Appendix: Artifact Numbering Convention

The CODITECT Bioscience QMS platform uses a legacy sequential numbering system (01-75+) alongside semantic naming for new B.1/B.2 artifacts.

Legacy Numbered Artifacts: 01-75 (assigned chronologically) Semantic Named Artifacts: market-sizing.md, competitive-landscape.md, gtm-foundation.md, etc. (B.1/B.2 generation)

Future Recommendation: Transition to semantic naming for all new artifacts to improve discoverability. Numbers are hard to remember; market-sizing.md is self-documenting.


This register is the single source of truth for artifact dependencies and cascade update requirements. After any context compaction, read this document first to understand what needs updating.


Copyright 2026 AZ1.AI Inc. All rights reserved. Developer: Hal Casteel, CEO/CTO Product: CODITECT-BIO-QMS | Part of the CODITECT Product Suite Classification: Internal - Confidential